The research was published online in Mayo Clinic Proceedings on 17 September and will appear in an upcoming print issue.

The meta-analysis, which compiles data from the complete body of scientific evidence — 40 clinical trials representing more than 135,000 study participants — found that EPA+DHA supplementation is associated with statistically significant risk reductions in several cardiovascular outcomes:

• 35% reduced risk of fatal myocardial infarction (MI)
• 13% reduced risk of MI
• 10% reduced risk of coronary heart disease (CHD) events
• 9% reduced risk of CHD mortality.

Notably, the protective effect increases with dosage. An additional 1 g/day of EPA+DHA results in an additional

• 5.8% reduction in the risk of CVD events (study results included dosages up to 5.5 g/day.)
• 9.0% reduction in the risk of MI (as above).

The articles first author is GOEDs Vice President of Data Science, Aldo Bernasconi, PhD. Article coauthors include Dr Carl "Chip" LaVie, a cardiologist at the John Ochsner Heart and Vascular Institute in New Orleans, LA, and epidemiological statistician Michelle Wiest, PhD, of the University of Idaho. 

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